Creation and annihilation of topological defects are prevalent in active materials. It is now shown that in living systems with nematic order, polar propulsion breaks mirror symmetry during these processes. ↧ Irreversibility and symmetry breaking in the creation and annihilat... Nature Physics - Creation and annihilation of topological defects are prevalent in active materials. It is now shown that in living systems with nematic order, polar propulsion breaks mirror...