$CRBU vs $LPCN: Contrasting Paths for Two Small-Cap Biotech Names CRBU (Caribou Biosciences) recently announced it would discontinue its two CAR-T cell therapy programs and explore strategic alternatives, triggering a sharp sell-off. LPCN (Lipocine) gained a near-term catalyst after Health Canada approved its oral testosterone therapy, TLANDO, lifting shares in recent trading. Both are small-cap, clinical-stage biopharmaceutical companies, but their recent trajectories and risk profiles have diverged sharply.